Effect of 17α-ethinylestradiol, levonorgestrel, 3-keto-desogestrel, and gestodene on calcium influx via voltage-gated calcium channels in human aortic smooth …
H Seeger, AO Mueck, G Lorkowski, AT Teichmann… - Contraception, 1996 - Elsevier
The effect of the synthetic estradiol, 17α-ethinylestradiol, and three progestogens on calcium
influx was investigated in cell cultures of human aortic smooth muscle. Neither the synthetic
estrogen nor the progestogens levonorgestrel, 3-keto-desogestrel, and gestodene showed,
in the concentration range of 10− 9 to 10− 6 M, a significant effect on calcium influx both
alone or in equimolar estrogen-gestagen combinations. The results indicate that these
substances, commonly used in contraceptive pills, do not change vasotonus interfering with …
influx was investigated in cell cultures of human aortic smooth muscle. Neither the synthetic
estrogen nor the progestogens levonorgestrel, 3-keto-desogestrel, and gestodene showed,
in the concentration range of 10− 9 to 10− 6 M, a significant effect on calcium influx both
alone or in equimolar estrogen-gestagen combinations. The results indicate that these
substances, commonly used in contraceptive pills, do not change vasotonus interfering with …